To put in short, I think she is unlikely. She will probably get Assist treatment like Shovel Knight. I have been keeping a close, but far eye on the series ever since I saw her games featured in a physical Nintendo Power issue. Her lack of a legacy prior to Risky's Revenge makes me think Sakurai will not seriously consider her at all. I don't think Western indies in particular are happening anytime soon. Western third-parties are much more likely to happen IMO.